Method for Qualitative Determination of 2-Deoxystreptamine
نویسندگان
چکیده
منابع مشابه
Method for qualitative determination of 2-deoxystreptamine.
We have developed a qualitative method to assay for the presence of 2-deoxystreptamine in hydrolysates of crude aminoglycoside preparations using a 2-deoxystreptamine-requiring idiotrophic mutant. The assay involves (i) incubation of a 2-deoxystreptamine-requiring mutant with 1 mg of a hydrolyzed preparation from a crude unknown antibiotic mixture per ml, and (ii) examination of the resultant i...
متن کامل2-Deoxystreptamine: central scaffold of aminoglycoside antibiotics.
A key structural feature of the aminoglycoside antibiotics is a 1,3-diaminocyclohexanetriol termed streptamine or, in cases where the 2-hydroxy function is deoxygenated as in most aminoglycosides, 2-deoxystreptamine. This central position of 2-deoxystreptamine suggests a crucial role for the biological activity of the aminoglycosides, that form a large class of clinically important antibiotics ...
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چکیده با توسعه شهر نشینی و دخل و تصرف غیر مجاز در حریم رودخانه ها خسارات زیادی به رودخانه و محیط زیست اطراف آن وارده می شود. در حال حاضر بر اساس آئین نامه اصلاح شده بستر و حریم رودخانه ها، حریم کمی رودخانه که بلافاصله پس از بستر قرار می گیرد از 1 تا20 متر از منتهی الیه طرفین بستر رودخانه تعیین، که مقدار دقیق آن در هر بازه از رودخانه مشخص نیست. در کشورهای دیگر روشهای متفاوتی من جمله: درصد ریسک...
15 صفحه اولStructure elucidation of an intermediate of 2-deoxystreptamine biosynthesis.
The structure of a 2-deoxystreptamine (DOS) precursor named S-11-P, which was isolated by using a DOS negative mutant derived from a xylostasin-producing strain of Bacillus circulans B15M, has been elucidated as (1 L)-1,3,5/2,4,-5-aminocyclohexanetetrol by comparison with an authentic specimen, which was synthesized from kanamycin A.
متن کاملQualitative and Quantitative Approaches for Determination of Hemolyzed Serum
Abstract Background and Objective: Prevention of medical laboratory errors is a major goal of quality control programs. Hemolyzed specimen is one of the common issues causing medical laboratory errors. Apart from the visual assessment, the measurement of serum hemoglobin concentration can be another method to evaluate the intensity of hemolysis. We aimed to assess hemolyzed serum s...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1978
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.14.1.157